Ethanolamine → HCID 17932884, compound

HRID 270299Notes

Reaction equation

HRID 270299 reaction equation
Br[CH2:2][CH2:3][CH2:4][CH2:5][O:6][C:7]1[CH:22]=[CH:21][C:10]2[C:11]([C:14]3[CH:19]=[CH:18][C:17]([Br:20])=[CH:16][CH:15]=3)=[N:12][S:13][C:9]=2[CH:8]=1.[CH2:23]([CH2:25][NH2:26])[OH:24]>>[Br:20][C:17]1[CH:18]=[CH:19][C:14]([C:11]2[C:10]3[CH:21]=[CH:22][C:7]([O:6][CH2:5][CH2:4][CH2:3][CH2:2][NH:26][CH2:25][CH2:23][OH:24])=[CH:8][C:9]=3[S:13][N:12]=2)=[CH:15][CH:16]=1

Participants

3

Reactant 2

HCID 700EthanolamineHCID 22313931HCID 22313931, compound

Product 1

HCID 17932884HCID 17932884, compound

Procedure

According to the method in example 6, 6-(4-Bromo-butoxy)-3-(4-bromo-phenyl)-benzo[d]isothiazole and ethanolamine were converted to yield 2-{4-[3-(4-Bromo-phenyl)-benzo[d]isothiazol-6-yloxy]-butylamino}-ethanol as white solid, MS: 421(MH+, 1Br).

Sources & evidence

ORD record
ord-3680f1cea7c645d985ce16321bfc2ab1
Source dataset
uspto-grants-2008_11
Patent number
US07449483B2

Reaction notes

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