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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 270306Generated: October 30, 2026

Piperidine → 3-(4-Chloro-phenyl)-6-(4-piperidin-1-yl-butoxy)-benzo[d]isothiazole

https://huagongshe.com/reaction/270306

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPiperidineHCID 8082—
Reactant6-(4-Bromo-butoxy)-3-(4-chloro-phenyl)-benzo[d]isothiazoleHCID 22313903—
Product3-(4-Chloro-phenyl)-6-(4-piperidin-1-yl-butoxy)-benzo[d]isothiazoleHCID 22314161—

Reaction Steps

According to the method in example 7, 6-(4-Bromo-butoxy)-3-(4-chloro-phenyl)-benzo[d]isothiazole and Piperidine were converted to yield 3-(4-Chloro-phenyl)-6-(4-piperidin-1-yl-butoxy)-benzo[d]isothiazole, MS: 401 (MH+, 1Cl).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07449483B2
Source datasetuspto-grants-2008_11
ORD IDord-3f9341a4cfb74b098790d6d8887d5fe3
Source noteuspto-grants-2008_11