Diethanolamine → 2-[{4-[3-(4-Chloro-phenyl)-benzo[d]isothiazol-6-yl]-butyl}-(2-hydroxy-ethyl)-amino]-ethanol

Participants

Role	Name	HCID	Charge
Reactant	Diethanolamine	HCID 8113	—
Reactant	Methanesulfonic acid 4-[3-(4-chloro-phenyl)-benzo[d]isothiazol-6-yl]-butyl ester	HCID 57428084	—
Product	2-[{4-[3-(4-Chloro-phenyl)-benzo[d]isothiazol-6-yl]-butyl}-(2-hydroxy-ethyl)-amino]-ethanol	HCID 22313963	—

Reaction Steps

According to the method in example 23, Methanesulfonic acid 4-[3-(4-chloro-phenyl)-benzo[d]isothiazol-6-yl]-butyl ester and Diethanolamin were converted to yield 2-[{4-[3-(4-Chloro-phenyl)-benzo[d]isothiazol-6-yl]-butyl}-(2-hydroxy-ethyl)-amino]-ethanol, MS: 405 (MH+, 1Cl).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07449483B2
Source dataset	uspto-grants-2008_11
ORD ID	ord-b05769c9f37c43b781596837b413fcd0
Source note	uspto-grants-2008_11