1,4-Dibromobutane → 6-(4-Bromo-butoxy)-3-(4-bromo-phenyl)-2-methyl-benzo[b]thiophene

HRID 270394Notes

Reaction equation

HRID 270394 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:9]3[CH:17]=[CH:16][C:15]([OH:18])=[CH:14][C:10]=3[S:11][C:12]=2[CH3:13])=[CH:4][CH:3]=1.[Br:19][CH2:20][CH2:21][CH2:22][CH2:23]Br>>[Br:19][CH2:20][CH2:21][CH2:22][CH2:23][O:18][C:15]1[CH:16]=[CH:17][C:9]2[C:8]([C:5]3[CH:6]=[CH:7][C:2]([Br:1])=[CH:3][CH:4]=3)=[C:12]([CH3:13])[S:11][C:10]=2[CH:14]=1

Participants

3

Reactant 2

HCID 80561,4-DibromobutaneHCID 223138873-(4-Bromo-phenyl)-2-methyl-benzo[b]thiophen-6-ol

Product 1

HCID 223139406-(4-Bromo-butoxy)-3-(4-bromo-phenyl)-2-methyl-benzo[b]thiophene

Procedure

In analogy to example 27.1, 3-(4-bromo-phenyl)-2-methyl-benzo[b]thiophen-6-ol and 1,4-dibromobutane were converted to yield 6-(4-bromo-butoxy)-3-(4-bromo-phenyl)-2-methyl-benzo[b]thiophene as colorless oil, MS: 452 (M, 2Br).

Sources & evidence

ORD record
ord-2721028c6b164cf682f721d6d622ce50
Source dataset
uspto-grants-2008_11
Patent number
US07449483B2

Reaction notes

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