Diethanolamine → 2-[{4-[3-(4-Bromo-phenyl)-benzo[b]thiophen-6-yloxy]-butyl}-(2-hydroxy-ethyl)-amino]-ethanol

Participants

Role	Name	HCID	Charge
Reactant	Diethanolamine	HCID 8113	—
Reactant	6-(4-Bromo-butoxy)-3-(4-bromo-phenyl)-benzo[b]thiophene	HCID 22314056	—
Product	2-[{4-[3-(4-Bromo-phenyl)-benzo[b]thiophen-6-yloxy]-butyl}-(2-hydroxy-ethyl)-amino]-ethanol	HCID 22314130	—

Reaction Steps

According to the method in example 29, 6-(4-Bromo-butoxy)-3-(4-bromo-phenyl)-benzo[b]thiophene and diethanolamine were converted to yield 2-[{4-[3-(4-Bromo-phenyl)-benzo[b]thiophen-6-yloxy]-butyl}-(2-hydroxy-ethyl)-amino]-ethanol as light yellow oil, MS: 464 (MH+, 1Br).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07449483B2
Source dataset	uspto-grants-2008_11
ORD ID	ord-c41e16d3ddd74bc3af544c4630c9e506
Source note	uspto-grants-2008_11