Dimethylamine → HCID 22314012, compound

HRID 270401Notes

Reaction equation

HRID 270401 reaction equation
Br[CH2:2][CH2:3][CH2:4][O:5][C:6]1[CH:7]=[CH:8][C:9]2[C:13]([C:14]3[CH:19]=[CH:18][C:17]([F:20])=[CH:16][CH:15]=3)=[CH:12][S:11][C:10]=2[CH:21]=1.[CH3:22][NH:23][CH3:24]>>[F:20][C:17]1[CH:18]=[CH:19][C:14]([C:13]2[C:9]3[CH:8]=[CH:7][C:6]([O:5][CH2:4][CH2:3][CH2:2][N:23]([CH3:24])[CH3:22])=[CH:21][C:10]=3[S:11][CH:12]=2)=[CH:15][CH:16]=1

Participants

3

Reactant 2

HCID 674DimethylamineHCID 223140346-(3-Bromo-propoxy)-3-(4-fluoro-phenyl)-benzo[b]thiophene

Product 1

HCID 22314012HCID 22314012, compound

Procedure

In analogy to example 3.1, 6-(3-Bromo-propoxy)-3-(4-fluoro-phenyl)-benzo[b]thiophene and dimethylamine were converted to yield {3-[3-(4-Fluoro-phenyl)-benzo[b]thiophen-6-yloxy]-propyl}-dimethyl-amine as colorless oil, MS: 330 (MH+).

Sources & evidence

ORD record
ord-76e9502cf57b4b8691c88f733770272d
Source dataset
uspto-grants-2008_11
Patent number
US07449483B2

Reaction notes

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