HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyrrolidine → 3-[3-(4-Fluoro-phenyl)-benzo[b]thiophen-6-yloxy]-propyl-pyrrolidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | 6-(3-Bromo-propoxy)-3-(4-fluoro-phenyl)-benzo[b]thiophene | HCID 22314034 | — |
| Product | 3-[3-(4-Fluoro-phenyl)-benzo[b]thiophen-6-yloxy]-propyl-pyrrolidine | HCID 22314006 | — |
Reaction Steps
In analogy to example 3.1, 6-(3-Bromo-propoxy)-3-(4-fluoro-phenyl)-benzo[b]thiophene and pyrrolidine were converted to yield 1-{3-[3-(4-Fluoro-phenyl)-benzo[b]thiophen-6-yloxy]-propyl}-pyrrolidine as colorless oil, MS: 356 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07449483B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-d577cf0a7f83485988474211d21c444e |
| Source note | uspto-grants-2008_11 |