HuagongsheHuagongshe Chemistry Print Report · For research reference only
Azetidine → 1-{3-[3-(4-Fluoro-phenyl)-benzo[b]thiophen-6-yloxy]-propyl}-azetidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Azetidine | HCID 10422 | — |
| Reactant | 6-(3-Bromo-propoxy)-3-(4-fluoro-phenyl)-benzo[b]thiophene | HCID 22314034 | — |
| Product | 1-{3-[3-(4-Fluoro-phenyl)-benzo[b]thiophen-6-yloxy]-propyl}-azetidine | HCID 22313947 | — |
Reaction Steps
In analogy to example 3.1, 6-(3-Bromo-propoxy)-3-(4-fluoro-phenyl)-benzo[b]thiophene and azetidine were converted to yield 1-{3-[3-(4-Fluoro-phenyl)-benzo[b]thiophen-6-yloxy]-propyl}-azetidine as colorless oil, MS: 342 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07449483B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-74a7d93304b54ba0a330f1361e17c761 |
| Source note | uspto-grants-2008_11 |