Bis(2-Methoxyethyl)amine → {4-[3-(4-Fluoro-phenyl)-benzo[b]thiophen-6-yloxy]-butyl}-bis-(2-methoxy-ethyl)-amine

Participants

Role	Name	HCID	Charge
Reactant	Bis(2-Methoxyethyl)amine	HCID 2383	—
Reactant	6-(4-Bromo-butoxy)-3-(4-fluoro-phenyl)-benzo[b]thiophene	HCID 22313938	—
Product	{4-[3-(4-Fluoro-phenyl)-benzo[b]thiophen-6-yloxy]-butyl}-bis-(2-methoxy-ethyl)-amine	HCID 22313891	—

Reaction Steps

In analogy to example 3.1, 6-(4-Bromo-butoxy)-3-(4-fluoro-phenyl)-benzo[b]thiophene and bis(2-methoxyethyl)amine were converted to yield {4-[3-(4-Fluoro-phenyl)-benzo[b]thiophen-6-yloxy]-butyl}-bis-(2-methoxy-ethyl)-amine as colorless oil, MS: 432 (MH+).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07449483B2
Source dataset	uspto-grants-2008_11
ORD ID	ord-fdecc55d05db42eaa88b23f5257539e3
Source note	uspto-grants-2008_11