HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Ethylamino)ethanol → 2-(Ethyl-{4-[2-methyl-3-(4-trifluoromethyl-phenyl)-benzo[b]thiophen-6-yloxy]-butyl}-amino)-ethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Ethylamino)ethanol | HCID 8072 | — |
| Reactant | 6-(4-Bromo-butoxy)-2-methyl-3-(4-trifluoromethyl-phenyl)-benzo[b]thiophene | HCID 22314148 | — |
| Product | 2-(Ethyl-{4-[2-methyl-3-(4-trifluoromethyl-phenyl)-benzo[b]thiophen-6-yloxy]-butyl}-amino)-ethanol | HCID 22314092 | — |
Reaction Steps
According to the method in example 31, 6-(4-Bromo-butoxy)-2-methyl-3-(4-trifluoromethyl-phenyl)-benzo[b]thiophene and 2-ethylamino-ethanol were converted to yield 2-(Ethyl-{4-[2-methyl-3-(4-trifluoromethyl-phenyl)-benzo[b]thiophen-6-yloxy]-butyl}-amino)-ethanol as yellowish oil, MS: 452 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07449483B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-df64505c1d5442ceb5299ecad47a8ec8 |
| Source note | uspto-grants-2008_11 |