N-(2-Methoxyethyl)ethylamine → HCID 22314153, compound

HRID 270431Notes

Reaction equation

HRID 270431 reaction equation
Br[CH2:2][CH2:3][CH2:4][CH2:5][O:6][C:7]1[CH:8]=[CH:9][C:10]2[C:14]([C:15]3[CH:20]=[CH:19][C:18]([Br:21])=[CH:17][CH:16]=3)=[C:13]([CH3:22])[S:12][C:11]=2[CH:23]=1.[CH3:24][O:25][CH2:26][CH2:27][NH:28][CH2:29][CH3:30]>>[Br:21][C:18]1[CH:19]=[CH:20][C:15]([C:14]2[C:10]3[CH:9]=[CH:8][C:7]([O:6][CH2:5][CH2:4][CH2:3][CH2:2][N:28]([CH2:29][CH3:30])[CH2:27][CH2:26][O:25][CH3:24])=[CH:23][C:11]=3[S:12][C:13]=2[CH3:22])=[CH:16][CH:17]=1

Participants

3

Reactant 2

HCID 546877N-(2-Methoxyethyl)ethylamineHCID 223139406-(4-Bromo-butoxy)-3-(4-bromo-phenyl)-2-methyl-benzo[b]thiophene

Product 1

HCID 22314153HCID 22314153, compound

Procedure

According to the method in example 31, 6-(4-Bromo-butoxy)-3-(4-bromo-phenyl)-2-methyl-benzo[b]thiophene and N-(2-methoxy-ethyl)-ethylamine were converted to yield {4-[3-(4-Bromo-phenyl)-2-methyl-benzo[b]thiophen-6-yloxy]-butyl}-ethyl-(2-methoxy-ethyl)-amine as yellowish oil, MS: 476 (MH+, 1Br).

Sources & evidence

ORD record
ord-73bd89536f784b359a5865b63bf62935
Source dataset
uspto-grants-2008_11
Patent number
US07449483B2

Reaction notes

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