1-Butyne, 3-chloro-3-methyl- → (1,1-Dimethyl-prop-2-ynyl)-ethyl-(2-methoxy-ethyl)-amine

HRID 270440Notes

Reaction equation

HRID 270440 reaction equation
Cl[C:2]([CH3:6])([CH3:5])[C:3]#[CH:4].[CH3:7][O:8][CH2:9][CH2:10][NH:11][CH2:12][CH3:13]>>[CH3:5][C:2]([N:11]([CH2:12][CH3:13])[CH2:10][CH2:9][O:8][CH3:7])([CH3:6])[C:3]#[CH:4]

Participants

3

Reactant 2

HCID 706791-Butyne, 3-chloro-3-methyl-HCID 546877N-(2-Methoxyethyl)ethylamine

Product 1

HCID 22314079(1,1-Dimethyl-prop-2-ynyl)-ethyl-(2-methoxy-ethyl)-amine

Procedure

In analogy to example 37.1, 3-Chloro-3-methyl-1-butyne and N-(2-Methoxyethyl)ethylamine were converted to yield (1,1-Dimethyl-prop-2-ynyl)-ethyl-(2-methoxy-ethyl)-amine as colorless oil, MS: 170 (MH+).

Sources & evidence

ORD record
ord-10d2e28bf0a545efb24c1439deeeedaa
Source dataset
uspto-grants-2008_11
Patent number
US07449483B2

Reaction notes

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