HuagongsheHuagongshe Chemistry Print Report · For research reference only
Allyl-(1-ethynyl-cyclopentyl)-methyl-amine → Allyl-methyl-{1-[3-(4-trifluoromethyl-phenyl)-benzo[d]isothiazol-6-ylethynyl]-cyclopentyl}-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Allyl-(1-ethynyl-cyclopentyl)-methyl-amine | HCID 22313997 | — |
| Reactant | Trifluoro-methanesulfonic acid 3-(4-trifluoromethyl-phenyl)-benzo[d]isothiazol-6-yl ester | HCID 57428077 | — |
| Product | Allyl-methyl-{1-[3-(4-trifluoromethyl-phenyl)-benzo[d]isothiazol-6-ylethynyl]-cyclopentyl}-amine | HCID 22313941 | — |
Reaction Steps
In analogy to example 14.1, Trifluoro-methanesulfonic acid 3-(4-trifluoromethyl-phenyl)-benzo[d]isothiazol-6-yl ester and Allyl-(1-ethynyl-cyclopentyl)-methyl-amine were converted to yield Allyl-methyl-{1-[3-(4-trifluoromethyl-phenyl)-benzo[d]isothiazol-6-ylethynyl]-cyclopentyl}-amine as light yellow oil, MS: 441 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07449483B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-0cf8a729ddce465fa1085b9b209008a3 |
| Source note | uspto-grants-2008_11 |