Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 270541Generated: October 30, 2026

Trifluoroacetic acid → HCID 86633368, compound

https://huagongshe.com/reaction/270541

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 59833538HCID 59833538—
SolventDichloromethaneHCID 6344—
ProductHCID 86633368HCID 86633368—

Reaction Steps

tert-Butyl [(1R,3S)-3-isopropyl-3-({4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}carbonyl)cyclopentyl]carbamate (82 mg, 0.18 mmol) was treated with trifluoroacetic acid (3 mL) in methylene chloride (3 mL) for 1 h at room temperature. The mixture was concentrated and used for next step without purification. MS calculated for C20H28F3N3O: (M+H) 383; found 383.2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07449467B2
Source datasetuspto-grants-2008_11
ORD IDord-065b7cd3783d408bb4dd0f7e4527e775
Source noteuspto-grants-2008_11