HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 86633368, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 59833538 | HCID 59833538 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 86633368 | HCID 86633368 | — |
Reaction Steps
tert-Butyl [(1R,3S)-3-isopropyl-3-({4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}carbonyl)cyclopentyl]carbamate (82 mg, 0.18 mmol) was treated with trifluoroacetic acid (3 mL) in methylene chloride (3 mL) for 1 h at room temperature. The mixture was concentrated and used for next step without purification. MS calculated for C20H28F3N3O: (M+H) 383; found 383.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07449467B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-065b7cd3783d408bb4dd0f7e4527e775 |
| Source note | uspto-grants-2008_11 |