tert-Butyl 4-(trifluoromethyl)-3',6'-dihydro-2,4'-bipyridine-1'(2'H)-carboxylate → HCID 59833569, compound

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Reaction Steps

tert-Butyl 4-(trifluoromethyl)-3′,6′-dihydro-2,4′-bipyridine-1′(2′H)-carboxylate (380.0 mg, 1.157 mmol) was dissolved in a 4 M solution of HCl in 1,4-dioxane (12.0 mL) to form a light yellow clear (then cloudy) solution. After being stirred at room temperature for 1 h, the reaction mixture was concentrated in vacuo to afford 389 mg of product as a yellow gum. LC-MS calculated for C11H11F3N2: (M+H) 229; found 229.1.

Provenance & Evidence