Cyclopropylamine → HCID 86589545, compound

HRID 270719Notes

Reaction equation

HRID 270719 reaction equation
Cl[C:2]1[C:7]([C:8](OCC)=[S:9])=[CH:6][N:5]=[C:4]([CH3:13])[N:3]=1.[CH:14]1([NH2:17])[CH2:16][CH2:15]1>>[CH:14]1([NH:17][C:2]2[C:7]([CH:8]=[S:9])=[CH:6][N:5]=[C:4]([CH3:13])[N:3]=2)[CH2:16][CH2:15]1

Participants

3

Reactant 2

HCID 69828CyclopropylamineHCID 53249641Ethyl 4-chloro-2-methylthio-pyrimidine-5-carboxylate

Product 1

HCID 86589545HCID 86589545, compound

Procedure

The 4-cyclopropylamino-2-methylthiopyrimidine-5-carboxaldehyde was prepared as described in Example 1 (steps A through C) starting with ethyl 4-chloro-2-methylthiopyrimidine-5-carboxylate (Aldrich Chemical Co.) and cyclopropyl amine (Aldrich Chemical Co.).

Sources & evidence

ORD record
ord-3cf8db475b104a49a5d494809142c0ee
Source dataset
uspto-grants-2008_11
Patent number
US07449581B2

Reaction notes

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