関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Dimethylformamide | HCID 6228 | — |
| 反応物 | Chlorosuccinimide | HCID 31398 | — |
| 反応物 | 1H-Pyrazole, 3-methyl-5-(trifluoromethyl)- | HCID 139077 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | HCID 178434610 | HCID 178434610 | — |
反応手順
3-methyl-5-trifluoromethylpyrazole was taken into dry DMF (20 mL) and N-chloro succinimide (1.78 g) was added in portions. The mixture was then heated at 70° C. for 22 h, cooled to room temperature, and then water (100 mL) was added and the mixture extracted with ethyl acetate (4×25 mL). The organic layer was washed with water and brine and dried with Na2SO4. Evaporation of the solvent afforded the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US07449576B1 |
|---|
| 出典データセット | uspto-grants-2008_11 |
|---|
| ORD ID | ord-54f8eead3ef64bd1b4ef90c1484c3d55 |
|---|
| 出典メモ | uspto-grants-2008_11 |
|---|
