Chlorosuccinimide → HCID 21071132, compound

Participants

Reaction Conditions

Reaction Steps

Following protocol L, a the solution of 3,5-diisopropyl-pyrazole (0.5 g, 3.57 mmol) in DMF (10 mL) was added NCS (0.72 g, 5.3 mmol) in portions under vigorous stirring. The reaction mixture was then heated at 80° C. for 14 h and then the reaction was quenched with water. It was then extracted with ethyl acetate (2×30 mL). The combined organics were washed with brine. The organic extracts were combined and dried with Na2SO4 and finally evaporated to give the title compound as colorless oil.

Provenance & Evidence