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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 270798Generated: October 26, 2026

Chlorosuccinimide → 4-chloro-3,5-bis(trifluoromethyl)-1H-pyrazole

https://huagongshe.com/reaction/270798

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChlorosuccinimideHCID 31398—
Reactant3,5-Bis(trifluoromethyl)pyrazoleHCID 518991—
SolventAcetonitrileHCID 6342—
Product4-chloro-3,5-bis(trifluoromethyl)-1H-pyrazoleHCID 10198633—

Reaction Steps

Following protocol L, 3,5-bistrifluoromethyl-1H-pyrazole was treated with NCS in CH3CN to yield the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07449576B1
Source datasetuspto-grants-2008_11
ORD IDord-3fcd5a3837ec4b2b8ae996ce757c97e3
Source noteuspto-grants-2008_11