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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 270804Generated: October 30, 2026

N-(3-methoxyphenyl)piperazine → HCID 21071083, compound

https://huagongshe.com/reaction/270804

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(3-methoxyphenyl)piperazineHCID 81430—
Reactant(4-Chloro-5-methyl-3-trifluoromethyl-pyrazol-1-yl)-acetic acidHCID 1876853—
ProductHCID 21071083HCID 21071083—

Reaction Steps

Title compound was prepared following protocol P, wherein 1-(3-methoxyphenyl)piperazine and (4-Chloro-5-methyl-3-trifluoromethyl-pyrazol-1-yl)-acetic acid were used as the coupling components, to give the product as a white solid: 1H NMR (DMSO-d6, 400 MHz) 7.15 (t, 1H), 6.65 (d, 1H), 6.60 (s, 1H), 6.47 (d, 1H), 5.38 (s, 2H), 3.72 (s, 3H), 3.65 (m, 4H), 3.28 (m, 2H), 3.19 (m, 2H), 2.18 (s, 3H) ppm; MS (ES) M+H expect=417.1, found=417.1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07449576B1
Source datasetuspto-grants-2008_11
ORD IDord-8ce5677ee0a04361b4335b110ffb6189
Source noteuspto-grants-2008_11