HRID270944

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：Cc1nc(C)c(COc2ccc(-c3cnc4c(C#N)cnn4c3C3CCCCC3)cc2)s1

HCID18445881

未命名化合物

结构：Cc1nc(C)c(COc2ccc(-c3cnc4c(-c5nnn[nH]5)cnn4c3C3CCCCC3)cc2)s1.c1nnn[nH]1

HCID178432760

未命名化合物

PRODUCTS

生成物

结构：Cc1nc(C)c(COc2ccc(-c3cnc4c(-c5nnn[nH]5)cnn4c3C3CCCCC3)cc2)s1

HCID178432759

未命名化合物

PROCEDURE

实验过程

Conversion of 7-cyclohexyl-6-[4-(2,4-dimethyl-thiazol-5-ylmethoxy)-phenyl]-pyrazolo[1,5-a]pyrimidine-3-carbonitrile to the corresponding tetrazole 7-cyclohexyl-6-[4-(2,4-dimethyl-thiazol-5-ylmethoxy)-phenyl]-3-(1H-tetrazol-5-yl)-pyrazolo[1,5-a]pyrimidine (358) was accomplished via a procedure described elsewhere.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-6320893899b14e3fb4eb3b51ebfe3816
来源数据集: uspto-grants-2008_11
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07449488B2
来源说明: uspto-grants-2008_11

反应 SMILES

C1(C2N3N=CC(C#N)=C3N=CC=2C2C=CC(OCC3SC(C)=NC=3C)=CC=2)CCCCC1.[CH:33]1([C:39]2[N:44]3[N:45]=[CH:46][C:47]([C:48]4[NH:52][N:51]=[N:50][N:49]=4)=[C:43]3[N:42]=[CH:41][C:40]=2[C:53]2[CH:58]=[CH:57][C:56]([O:59][CH2:60][C:61]3[S:65][C:64]([CH3:66])=[N:63][C:62]=3[CH3:67])=[CH:55][CH:54]=2)[CH2:38][CH2:37][CH2:36][CH2:35][CH2:34]1.N1C=NN=N1>>[CH:33]1([C:39]2[N:44]3[N:45]=[CH:46][C:47]([C:48]4[NH:49][N:50]=[N:51][N:52]=4)=[C:43]3[N:42]=[CH:41][C:40]=2[C:53]2[CH:58]=[CH:57][C:56]([O:59][CH2:60][C:61]3[S:65][C:64]([CH3:66])=[N:63][C:62]=3[CH3:67])=[CH:55][CH:54]=2)[CH2:34][CH2:35][CH2:36][CH2:37][CH2:38]1