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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 270946Generated: October 30, 2026

7-Cyclohexyl-6-[4-(3-trifluoromethyl-benzyloxy)-phenyl]-pyrazolo[1,5-a]pyrimidine-3-carbonitrile → HCID 178506161, compound

https://huagongshe.com/reaction/270946

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-Cyclohexyl-6-[4-(3-trifluoromethyl-benzyloxy)-phenyl]-pyrazolo[1,5-a]pyrimidine-3-carbonitrileHCID 18445883—
ReactantHCID 178506162HCID 178506162—
ProductHCID 178506161HCID 178506161—

Reaction Steps

Conversion of 7-cyclohexyl-6-[4-(3-trifluoromethyl-benzyloxy)-phenyl]-pyrazolo[1,5-a]pyrimidine-3-carbonitrile to the corresponding tetrazole 7-cyclohexyl-3-(1H-tetrazol-5-yl)-6-[4-(3-trifluoromethyl-benzyloxy)-phenyl]-pyrazolo[1,5-a]pyrimidine (331) was accomplished via a procedure described elsewhere in this document.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07449488B2
Source datasetuspto-grants-2008_11
ORD IDord-3b79247188274d258c775d765f70eeda
Source noteuspto-grants-2008_11