HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Bicarbonate → HCID 59834356, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | HCID 59834364 | HCID 59834364 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | HCID 59834356 | HCID 59834356 | 95% |
Reaction Steps
A mixture of 1-[6-(2,4-difluorophenoxy)pyrazolo[4,3-c]pyridine-1-yl]ethanone (0.26 g) in 15 mL of 20% aqueous hydrochloric acid was heated for 3 hours on a steam bath, cooled, neutralized with NaHCO3, and extracted with CH2Cl2 to give 0.21 g of 6-(2,4-difluorophenoxy)-1H-pyrazolo[4,3-c]pyridine (95% yield). Mass Spec. M+H=248.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07452880B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-0b9bcc7efb9d4885b3e4c66be806e7c8 |
| Source note | uspto-grants-2008_11 |