Ethylamine → 1-Nitro-2-ethylamino-2-[2-(2-thiazolylmethylthio)ethylamino]ethylene

HRID 27112Notes

Reaction equation

HRID 27112 reaction equation
[N+:1]([CH:4]=[C:5](SC)[NH:6][CH2:7][CH2:8][S:9][CH2:10][C:11]1[S:12][CH:13]=[CH:14][N:15]=1)([O-:3])=[O:2].[CH2:18]([NH2:20])[CH3:19]>O>[N+:1]([CH:4]=[C:5]([NH:20][CH2:18][CH3:19])[NH:6][CH2:7][CH2:8][S:9][CH2:10][C:11]1[S:12][CH:13]=[CH:14][N:15]=1)([O-:3])=[O:2]

Participants

4

Reactant 2

HCID 6341EthylamineHCID 705429481-(Methylsulfanyl)-2-nitro-N-(2-{[(1,3-thiazol-2-yl)methyl]sulfanyl}ethyl)ethen-1-amine

Product 1

HCID 705440481-Nitro-2-ethylamino-2-[2-(2-thiazolylmethylthio)ethylamino]ethylene

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Reaction of 1-nitro-2-methylthio-2-[2-(2-thiazolylmethylthio)ethylamino]ethylene (see Example 55(i)) with ethylamine by the procedure of Example 8(ii) gives the title product, m.p. 115°-116° (from water).

Sources & evidence

ORD record
ord-c371f797e1dd48d1b810cd8e54c47b3c
Source dataset
uspto-grants-1980_09
Patent number
US04220652

Reaction notes

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