HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aniline → 2-[(N-phenylcarbamoyl)methyl]prop-2-enoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aniline | HCID 6115 | — |
| Reactant | Itaconic Anhydride | HCID 75110 | — |
| Solvent | Methyl Chloride | HCID 6327 | — |
| Product | 2-[(N-phenylcarbamoyl)methyl]prop-2-enoic acid | HCID 21935560 | — |
Reaction Steps
A solution of 2-methylenesuccinic anhydride (500 mg, 4.46 mmol) and aniline (0.4 mL, 4.46 mmol) in CH3Cl were shaken overnight. A precipitate formed, which was filtered off, washed with hexanes, and dried under vacuum to afford 2-[(N-phenylcarbamoyl)methyl]prop-2-enoic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07452889B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-682c33e9511d4681b3e6095fa4659f39 |
| Source note | uspto-grants-2008_11 |