Dimethylamine → HCID 59834997, compound

Participants

Reaction Steps

A solution of ethyl 2-chloro-6-(2-furyl)-9H-purine-9-acetate (100 mg, 0.33 mol) in isopropanol (1 mL) was treated with 40% dimethylamine in water, refluxed for 2 h, cooled, poured into water, extracted with EtOAc and the combined organic phase dried (MgSO4), concentrated in vacuo and purified by chromatography [SiO2; Heptane:EtOAc, (1:1)] to give the title compound (20 mg, 19%) as a white solid.

Provenance & Evidence