Aniline → HCID 59834956, compound

Participants

Reaction Steps

A solution of 2-amino-6-(2-furyl)-9H-purine-9-acetic acid (129 mg, 0.5 mmol) in DCM (2 mL) was treated with EDCI (96 mg, 0.5 mmol) and aniline (45 μL, 0.5 mmol), stirred at room temperature for 3 days, diluted with DCM, washed with water, dried (MgSO4), concentrated in vacuo and purified by chromatography (SiO2; 1% MeOH in EtOAc) to give the title compound (51 mg, 31%) as a white solid.

Provenance & Evidence