反应详情

温度

100 °C

The mixture of 185 mg of 2,6-dichloro-4-cyanobenzoic acid methylester, 266 mg of azidotributyltin and 5 ml of toluene was stirred at 100° C. for 3 days. The reaction mixture was concentrated and diluted with ethyl acetate. After Celite filtration, the filtrate was concentrated and the residue was purified by reverse phase HPLC to obtain the title compound.

1. concentrationThe reaction mixture was concentrated
2. additiondiluted with ethyl acetate
3. filtrationAfter Celite filtration
4. concentrationthe filtrate was concentrated
5. customthe residue was purified by reverse phase HPLC