HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(Chloromethyl)-2-(trifluoromethyl)pyridine → 7,8-bis(4-chlorophenyl)-5-methyl-2-((6-(trifluoromethyl)pyridin-3-yl)methyl)-[1,2,4]triazolo[4,3-c]pyrimidin-3(2H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(Chloromethyl)-2-(trifluoromethyl)pyridine | HCID 2773810 | — |
| Reactant | 7,8-bis(4-chlorophenyl)-5-methyl-2-(4-(trifluoromethyl)benzyl)-[1,2,4]triazolo[4,3-c]pyrimidin-3(2H)-one | HCID 15953281 | — |
| Reactant | 7,8-bis(4-chlorophenyl)-5-methyl-[1,2,4]triazolo[4,3-c]pyrimidin-3(2H)-one | HCID 58772842 | — |
| Product | 7,8-bis(4-chlorophenyl)-5-methyl-2-((6-(trifluoromethyl)pyridin-3-yl)methyl)-[1,2,4]triazolo[4,3-c]pyrimidin-3(2H)-one | HCID 15953282 | — |
Reaction Steps
The title compound was prepared by coupling 7,8-bis(4-chlorophenyl)-5-methyl-[1,2,4]triazolo[4,3-c]pyrimidin-3(2H)-one with 5-(chloromethyl)-2-(trifluoromethyl)pyridine in a manner analogous to that in which 7,8-bis(4-chlorophenyl)-5-methyl-2-(4-(trifluoromethyl)benzyl)-[1,2,4]triazolo[4,3-c]pyrimidin-3(2H)-one was prepared. HPLC/MS: retention time=4.188 min, [M+H]30 =530.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07452892B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-1fe4bfcc266f4e2d8103f632b101b72b |
| Source note | uspto-grants-2008_11 |