HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Chloride → HCID 15953283, Verbindung
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Chloride | HCID 312 | — |
| Edukt | Iodoethane | HCID 6340 | — |
| Edukt | HCID 15953281 | HCID 15953281 | — |
| Edukt | 5-chloro-7,8-bis(4-chlorophenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-3(2H)-one | HCID 58772840 | — |
| Edukt | HCID 178490612 | HCID 178490612 | — |
| Produkt | HCID 15953283 | HCID 15953283 | — |
Reaktionsschritte
The title compound was prepared in two steps from 5-chloro-7,8-bis(4-chlorophenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-3(2H)-one by nucleophilic displacement of chloride with 4-methoxybenzylzinc chloride, followed by alkylation with iodoethane, in a manner analogous to that in which 7,8-bis(4-chlorophenyl)-5-methyl-2-(4-(trifluoromethyl)benzyl)-[1,2,4]triazolo[4,3-c]pyrimidin-3(2H)-one was prepared. HPLC/MS: retention time=4.571 min, [M+H]30 =505.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07452892B2 |
| Quelldatensatz | uspto-grants-2008_11 |
| ORD ID | ord-1f3784382be6412da990ead040d0983a |
| Quellennotiz | uspto-grants-2008_11 |