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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 271443Erstellt: 25. Oktober 2026

Chloride → HCID 15953283, Verbindung

https://huagongshe.com/reaction/271443

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktChlorideHCID 312—
EduktIodoethaneHCID 6340—
EduktHCID 15953281HCID 15953281—
Edukt5-chloro-7,8-bis(4-chlorophenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-3(2H)-oneHCID 58772840—
EduktHCID 178490612HCID 178490612—
ProduktHCID 15953283HCID 15953283—

Reaktionsschritte

The title compound was prepared in two steps from 5-chloro-7,8-bis(4-chlorophenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-3(2H)-one by nucleophilic displacement of chloride with 4-methoxybenzylzinc chloride, followed by alkylation with iodoethane, in a manner analogous to that in which 7,8-bis(4-chlorophenyl)-5-methyl-2-(4-(trifluoromethyl)benzyl)-[1,2,4]triazolo[4,3-c]pyrimidin-3(2H)-one was prepared. HPLC/MS: retention time=4.571 min, [M+H]30 =505.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07452892B2
Quelldatensatzuspto-grants-2008_11
ORD IDord-1f3784382be6412da990ead040d0983a
Quellennotizuspto-grants-2008_11