Methylamine → HCID 58772831, compound

Participants

Reaction Steps

To a stirring solution of 5-chloro-7,8-bis(4-chlorophenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-3(2H)-one (36 mg, 0.09 mmol) in 1 mL THF was added methylamine (2 M in THF, 0.13 mL, 0.26 mmol), followed by N,N-diisopropylethylamine (12 mg, 0.09 mmol). The reaction mixture was stirred at room temperature for 5 h and then concentrated under reduced pressure. The resulting crude title compound was used in the next step without further purification. HPLC/MS: retention time=4.06 min, [M+H]30 =386.

Provenance & Evidence