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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 271482Generated: October 25, 2026

6-Chloromethyl-2-methylpyridinium chloride → 3-[2-Methyl-1-(6-methyl-pyridin-2-ylmethyl)-1H-imidazol-4-ylethynyl]-benzonitrile

https://huagongshe.com/reaction/271482

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Chloromethyl-2-methylpyridinium chlorideHCID 76545—
ReactantHCID 178432699HCID 178432699—
Product3-[2-Methyl-1-(6-methyl-pyridin-2-ylmethyl)-1H-imidazol-4-ylethynyl]-benzonitrileHCID 67248044—

Reaction Steps

The title compound, MS: m/e=313.2 (M+H30), was prepared in accordance with the general method of example 1 from 3-(2-methyl-1H-imidazol-4-ylethynyl)-benzonitrile and 2-chloromethyl-6-methyl-pyridine hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07452909B2
Source datasetuspto-grants-2008_11
ORD IDord-89dd756eb32a486fa3345ca74b4d75d9
Source noteuspto-grants-2008_11