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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 271484Generated: October 26, 2026

2-(Chloromethyl)-3-methylpyridine hydrochloride → 4-[1-(3-Methyl-pyridin-2-ylmethyl)-2-methyl-1H-imidazol-4-ylethynyl]-2-methyl-pyridine

https://huagongshe.com/reaction/271484

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Chloromethyl)-3-methylpyridine hydrochlorideHCID 13058683—
ReactantHCID 178418884HCID 178418884—
Product4-[1-(3-Methyl-pyridin-2-ylmethyl)-2-methyl-1H-imidazol-4-ylethynyl]-2-methyl-pyridineHCID 67246055—

Reaction Steps

The title compound, MS: m/e=303.2 (M+H30), was prepared in accordance with the general method of example 1 from 2-methyl-4-(2-methyl-1H-imidazol-4-ylethynyl)-pyridine and 2-chloromethyl-3-methyl-pyridine hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07452909B2
Source datasetuspto-grants-2008_11
ORD IDord-a8da949f79a44b608f1605093ccef283
Source noteuspto-grants-2008_11