Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 271485Generated: October 26, 2026

2-(Chloromethyl)-3-methylpyridine hydrochloride → 3-[2-Methyl-1-(3-methyl-pyridin-2-ylmethyl)-1H-imidazol-4-ylethynyl]-benzonitrile

https://huagongshe.com/reaction/271485

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Chloromethyl)-3-methylpyridine hydrochlorideHCID 13058683—
ReactantHCID 178432699HCID 178432699—
Product3-[2-Methyl-1-(3-methyl-pyridin-2-ylmethyl)-1H-imidazol-4-ylethynyl]-benzonitrileHCID 67245612—

Reaction Steps

The title compound, MS: m/e=313.2 (M+H30), was prepared in accordance with the general method of example 1 from 3-(2-methyl-1H-imidazol-4-ylethynyl)-benzonitrile and 2-chloromethyl-3-methyl-pyridine hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07452909B2
Source datasetuspto-grants-2008_11
ORD IDord-59477f9010f14c83802da96288cee1de
Source noteuspto-grants-2008_11