Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 271494Generated: November 1, 2026

4-(Chloromethyl)-2-methylpyridine hydrochloride → 4-[1-(2-Methyl-pyridin-4-ylmethyl)-2-methyl-1H-imidazol-4-ylethynyl]-2-chloro-pyridine

https://huagongshe.com/reaction/271494

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Chloromethyl)-2-methylpyridine hydrochlorideHCID 22625044—
ReactantHCID 178418879HCID 178418879—
Product4-[1-(2-Methyl-pyridin-4-ylmethyl)-2-methyl-1H-imidazol-4-ylethynyl]-2-chloro-pyridineHCID 86596932—

Reaction Steps

The title compound, MS: m/e=323.3 (M+H30), was prepared in accordance with the general method of example 1 from 2-chloro-4-(2-methyl-1H-imidazol-4-ylethynyl)-pyridine and 4-chloromethyl-2-methyl-pyridine hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07452909B2
Source datasetuspto-grants-2008_11
ORD IDord-3b13882cc4fd41bcb39d8229596c0a45
Source noteuspto-grants-2008_11