4-Fluorobenzyl bromide → HCID 67247706, compound

HRID 271499Notes

Reaction equation

HRID 271499 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:15])[NH:13][CH:14]=2)[CH:5]=[CH:4][N:3]=1.[F:16][C:17]1[CH:24]=[CH:23][C:20]([CH2:21]Br)=[CH:19][CH:18]=1>>[F:16][C:17]1[CH:24]=[CH:23][C:20]([CH2:21][N:13]2[CH:14]=[C:10]([C:9]#[C:8][C:6]3[CH:5]=[CH:4][N:3]=[C:2]([CH3:1])[CH:7]=3)[N:11]=[C:12]2[CH3:15])=[CH:19][CH:18]=1

Participants

3

Reactant 2

HCID 680214-Fluorobenzyl bromideHCID 178418884HCID 178418884, compound

Product 1

HCID 67247706HCID 67247706, compound

Procedure

The title compound, MS: m/e=306.2 (M+H30), was prepared in accordance with the general method of example 1 from 2-methyl-4-(2-methyl-1H-imidazol-4-ylethynyl)-pyridine and 4-fluoro-benzylbromide.

Sources & evidence

ORD record
ord-23778c03c7ea4410a5b44967ebf3fb72
Source dataset
uspto-grants-2008_11
Patent number
US07452909B2

Reaction notes

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