4-(Bromomethyl)-1,2-difluorobenzene → HCID 67247857, compound

HRID 271500Notes

Reaction equation

HRID 271500 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([C:8]#[C:9][C:10]2[N:11]=[C:12]([CH3:15])[NH:13][CH:14]=2)[CH:5]=[CH:4][N:3]=1.[F:16][C:17]1[CH:18]=[C:19]([CH:22]=[CH:23][C:24]=1[F:25])[CH2:20]Br>>[F:16][C:17]1[CH:18]=[C:19]([CH:22]=[CH:23][C:24]=1[F:25])[CH2:20][N:13]1[CH:14]=[C:10]([C:9]#[C:8][C:6]2[CH:5]=[CH:4][N:3]=[C:2]([CH3:1])[CH:7]=2)[N:11]=[C:12]1[CH3:15]

Participants

3

Reactant 2

HCID 5814364-(Bromomethyl)-1,2-difluorobenzeneHCID 178418884HCID 178418884, compound

Product 1

HCID 67247857HCID 67247857, compound

Procedure

The title compound, MS: m/e=324.2 (M+H30), was prepared in accordance with the general method of example 1 from 2-methyl-4-(2-methyl-1H-imidazol-4-ylethynyl)-pyridine and 3,4-difluoro-benzylbromide.

Sources & evidence

ORD record
ord-a2bc3b905a2546278712afa6fdffc311
Source dataset
uspto-grants-2008_11
Patent number
US07452909B2

Reaction notes

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