Succinic anhydride → HCID 59834721, compound

Participants

Reaction Steps

To a solution of 6-(4-amino-benzyl)-7-(2,2-dimethyl-propyl)-7H-pyrrolo[2,3-d]pyrimidine-2-carbonitrile (0.626 mmol) in THF (3 ml), succinic anhydride (0.626 mmol) is added. The reaction mixture is stirred at room temperature for 16 h. The reaction mixture is concentrated under vacuum. Purification of the residue by silica gel column chromatography affords the title compound in quantitative yield.

Provenance & Evidence