HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzoyl Peroxide → 8-bromomethyl-9-(2,2-dimethyl-propyl)-9H-purine-2-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzoyl Peroxide | HCID 7187 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | 9-(2,2-dimethyl-propyl)-8-methyl-9H-purine-2-carbonitrile | HCID 17968214 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | 8-bromomethyl-9-(2,2-dimethyl-propyl)-9H-purine-2-carbonitrile | HCID 17968163 | — |
Reaction Steps
A mixture of 1.1 g 9-(2,2-dimethyl-propyl)-8-methyl-9H-purine-2-carbonitrile, 1.7 g of N-bromosuccinimide and 116 mg dibenzoylperoxide was heated for 18 hours under reflux in 5 ml of CCl4. The mixture was evaporated and the residue was chromatographed on silicagel using hexanes/ethylacetate yielding 8-bromomethyl-9-(2,2-dimethyl-propyl)-9H-purine-2-carbonitrile as pale yellow wax.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07452886B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-95a85bda824e4bb384af266a2c753a4a |
| Source note | uspto-grants-2008_11 |