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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 271641Generated: October 25, 2026

p-Chlorophenylboric acid → 4-(4-{4-[5-(4-Chloro-phenyl)-pyridin-2-yl]-but-3-ynyl}-benzyl)-morpholine

https://huagongshe.com/reaction/271641

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-Chlorophenylboric acidHCID 17810664—
Reactant4-{4-[4-(5-Bromo-pyridin-2-yl)-but-3-ynyl]-benzyl}-morpholineHCID 69079684—
Product4-(4-{4-[5-(4-Chloro-phenyl)-pyridin-2-yl]-but-3-ynyl}-benzyl)-morpholineHCID 10319779—

Reaction Steps

Prepared analogously to Example 2.20c from 90 mg (0.23 mmol) 4-{4-[4-(5-bromo-pyridin-2-yl)-but-3-ynyl]-benzyl}-morpholine and 73 mg (0.47 mmol) 4-chlorophenylboric acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07452911B2
Source datasetuspto-grants-2008_11
ORD IDord-08e7c81fdffb47e495b2d2e60d8c67aa
Source noteuspto-grants-2008_11