5-(4-Chloro-phenyl)-2-ethynyl-pyridine → HCID 10093392, compound

HRID 271655Notes

Reaction equation

HRID 271655 reaction equation
I[C:2]1[CH:3]=[C:4]([CH:14]=[CH:15][CH:16]=1)[O:5][CH2:6][CH2:7][CH2:8][N:9]1[CH2:13][CH2:12][CH2:11][CH2:10]1.[Cl:17][C:18]1[CH:23]=[CH:22][C:21]([C:24]2[CH:25]=[CH:26][C:27]([C:30]#[CH:31])=[N:28][CH:29]=2)=[CH:20][CH:19]=1>>[Cl:17][C:18]1[CH:19]=[CH:20][C:21]([C:24]2[CH:25]=[CH:26][C:27]([C:30]#[C:31][C:2]3[CH:16]=[CH:15][CH:14]=[C:4]([O:5][CH2:6][CH2:7][CH2:8][N:9]4[CH2:13][CH2:12][CH2:11][CH2:10]4)[CH:3]=3)=[N:28][CH:29]=2)=[CH:22][CH:23]=1

Participants

3

Reactant 2

HCID 578453285-(4-Chloro-phenyl)-2-ethynyl-pyridineHCID 61494114HCID 61494114, compound

Product 1

HCID 10093392HCID 10093392, compound

Procedure

Prepared according to general working method I from 1-[3-(3-iodo-phenoxy)-propyl]-pyrrolidine (124 mg, 0.37 mmol) and 5-(4-chloro-phenyl)-2-ethynyl-pyridine (80 mg, 0.37 mmol).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-3a0617afa99f45dc846d8799fb3dd7e1
Source dataset
uspto-grants-2008_11
Patent number
US07452911B2

Reaction notes

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