HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(4-Chloro-phenyl)-2-ethynyl-pyridine → {5-[5-(4-Chloro-phenyl)-pyridin-2-ylethynyl]-pyridin-2-yl}-(2-pyrrolidin-1-yl-ethyl)-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(4-Chloro-phenyl)-2-ethynyl-pyridine | HCID 57845328 | — |
| Reactant | 5-Bromo-N-[2-(pyrrolidin-1-yl)ethyl]pyridin-2-amine | HCID 62642748 | — |
| Product | {5-[5-(4-Chloro-phenyl)-pyridin-2-ylethynyl]-pyridin-2-yl}-(2-pyrrolidin-1-yl-ethyl)-amine | HCID 10250554 | — |
Reaction Steps
The product is obtained analogously to Example 3.16b is from 90 mg (0.33 mmol) (5-bromo-pyridin-2-yl)-(2-pyrrolidin-1-yl-ethyl)-amine and 88 mg (0.41 mmol) 5-(4-chloro-phenyl)-2-ethynyl-pyridine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07452911B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-b4a4da3e5f554b1480596bfab8d8fc4f |
| Source note | uspto-grants-2008_11 |