HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Bicarbonate → HCID 67364572, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | HCID 62642302 | HCID 62642302 | — |
| Solvent | Formic Acid | HCID 284 | — |
| Product | HCID 67364572 | HCID 67364572 | — |
Reaction Steps
A solution of 904 mg (3.18 mmol) 4-bromo-N1-(2-pyrrolidin-1-yl-ethyl)-benzene-1,2-diamine in 5 mL formic acid is refluxed for 1.5 h. It is made alkaline with semisaturated NaHCO3 solution and extracted twice with 70 mL EtOAc. The organic phase is dried over MgSO4 and the solvent is eliminated i.vac.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07452911B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-8ea180eea2264801af19f2c82a9cbae7 |
| Source note | uspto-grants-2008_11 |