5-(4-Chloro-phenyl)-2-ethynyl-pyridine → HCID 59835912, compound

HRID 271679Notes

Reaction equation

HRID 271679 reaction equation
I[C:2]1[CH:17]=[CH:16][C:5]2[N:6]([CH2:9][CH2:10][N:11]3[CH2:15][CH2:14][CH2:13][CH2:12]3)[CH:7]=[N:8][C:4]=2[CH:3]=1.[Cl:18][C:19]1[CH:24]=[CH:23][C:22]([C:25]2[CH:26]=[CH:27][C:28]([C:31]#[CH:32])=[N:29][CH:30]=2)=[CH:21][CH:20]=1>>[Cl:18][C:19]1[CH:20]=[CH:21][C:22]([C:25]2[CH:26]=[CH:27][C:28]([C:31]#[C:32][C:2]3[CH:17]=[CH:16][C:5]4[N:6]([CH2:9][CH2:10][N:11]5[CH2:15][CH2:14][CH2:13][CH2:12]5)[CH:7]=[N:8][C:4]=4[CH:3]=3)=[N:29][CH:30]=2)=[CH:23][CH:24]=1

Participants

3

Reactant 2

HCID 578453285-(4-Chloro-phenyl)-2-ethynyl-pyridineHCID 69079010HCID 69079010, compound

Product 1

HCID 59835912HCID 59835912, compound

Procedure

Prepared according to general working method I from 5-iodo-1-(2-pyrrolidin-1-yl-ethyl)-1H-benzimidazole (150 mg, 0.44 mmol) and 5-(4-chloro-phenyl)-2-ethynyl-pyridine (94 mg, 0.44 mmol).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-c99345673994493fa599514aa4cc7433
Source dataset
uspto-grants-2008_11
Patent number
US07452911B2

Reaction notes

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