5-(4-Chloro-phenyl)-2-ethynyl-pyridine → HCID 9979213, compound

HRID 271697Notes

Reaction equation

HRID 271697 reaction equation
I[C:2]1[CH:3]=[CH:4][C:5]2[S:14][C:13]3[CH2:12][CH2:11][NH:10][CH2:9][CH2:8][C:7]=3[C:6]=2[CH:15]=1.[Cl:16][C:17]1[CH:22]=[CH:21][C:20]([C:23]2[CH:24]=[CH:25][C:26]([C:29]#[CH:30])=[N:27][CH:28]=2)=[CH:19][CH:18]=1>>[Cl:16][C:17]1[CH:18]=[CH:19][C:20]([C:23]2[CH:24]=[CH:25][C:26]([C:29]#[C:30][C:2]3[CH:3]=[CH:4][C:5]4[S:14][C:13]5[CH2:12][CH2:11][NH:10][CH2:9][CH2:8][C:7]=5[C:6]=4[CH:15]=3)=[N:27][CH:28]=2)=[CH:21][CH:22]=1

Participants

3

Reactant 2

HCID 578453285-(4-Chloro-phenyl)-2-ethynyl-pyridineHCID 69073638HCID 69073638, compound

Product 1

HCID 9979213HCID 9979213, compound

Procedure

Prepared according to general working method I from 3-iodo-6,7,8,9-tetrahydro-5H-10-thia-7-aza-benzo[a]azulene (770 mg, 2.34 mmol) and 5-(4-chloro-phenyl)-2-ethynyl-pyridine (500 mg, 2.34 mmol).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-39263d1adcac4c8e81c7ff722b253171
Source dataset
uspto-grants-2008_11
Patent number
US07452911B2

Reaction notes

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