反应详情

To 20 g (0.93 mole) of the resulting N-(3-methylphenyl)-dimethyl-maleimide in 180 ml of methanol is added at 20° 7.2 g (0.185 mole) of sodium borohydride in portions so small that the temperature does not exceed 40°. An intense evolution of gas is observed. The reaction mixture is initially a clear colourless solution, but soon becomes a white suspension, which is poured after one hour into water. The white substance which has precipitated out is filtered off, washed well with methanol and dried under reduced pressure to obtain 18.6 g of white crystals (92.1% of theory), which melt at 170°-172° (compound No. 9, Table I).

1. customdoes not exceed 40°
2. customThe white substance which has precipitated out
3. filtrationis filtered off
4. washwashed well with methanol
5. customdried under reduced pressure