Propanal → HCID 69101013, compound

HRID 272082Notes

Reaction equation

HRID 272082 reaction equation
[NH:1]1[CH2:6][CH2:5][CH2:4][C@H:3]([CH2:7][NH:8][C:9]([C@H:11]2[CH2:15][CH2:14][CH2:13][N:12]2[C:16]([C@@H:18]2[CH2:22][CH2:21][CH2:20][N:19]2[C:23](=[O:44])[CH2:24][C:25]([C:38]2[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=2)([C:32]2[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=2)[C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)=[O:17])=[O:10])[CH2:2]1.[CH:45](=O)[CH2:46][CH3:47]>>[CH2:45]([N:1]1[CH2:6][CH2:5][CH2:4][C@H:3]([CH2:7][NH:8][C:9]([C@H:11]2[CH2:15][CH2:14][CH2:13][N:12]2[C:16]([C@@H:18]2[CH2:22][CH2:21][CH2:20][N:19]2[C:23](=[O:44])[CH2:24][C:25]([C:32]2[CH:33]=[CH:34][CH:35]=[CH:36][CH:37]=2)([C:38]2[CH:43]=[CH:42][CH:41]=[CH:40][CH:39]=2)[C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)=[O:17])=[O:10])[CH2:2]1)[CH2:46][CH3:47]

Participants

3

Reactant 2

HCID 527PropanalHCID 10984804HCID 10984804, compound

Product 1

HCID 69101013HCID 69101013, compound

Procedure

The title compound was prepared by a method similar to Step 3 of Example 17, using (2R)-N-((3S)-3-piperidylmethyl)-1-{(2S)-1-(3,3,3-triphenylpropanoyl)pyrrolidin-2-yl}carbonylpyrrolidine-2-carboxamide and propionaldehyde. The product was obtained as a white solid.

Workup

  1. customThe product was obtained as a white solid

Sources & evidence

ORD record
ord-9eb34b2be9084f6eb423a7a0726f63a6
Source dataset
uspto-grants-2008_11
Patent number
US07452908B2

Reaction notes

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