反应详情

3-Methylthio-6-(3-methoxybenzyl)-1,2,4-triazin-5-one (1.07 g) and 2-(5-methyl-4-imidazolylmethylthio)ethylamine (0.77 g) were heated together on an oil bath (160°-70°) for 3/4 hour. The solidified mass was broken up under methanol (ea 15 ml) and boiled for 5 minutes. After cooling the white solid was filtered off and recrystallised from dimethylformamide to give the title compound as a colourless solid (0.65 g) m.p. 203°-4°.

1. temperatureAfter cooling the white solid
2. filtrationwas filtered off
3. customrecrystallised from dimethylformamide