Acetic Acid → HCID 23344265, compound

HRID 27221Notes

Reaction equation

HRID 27221 reaction equation
[CH3:1][C:2]1([CH3:13])[CH2:7][C:6]([OH:10])([C:8]#[N:9])[CH2:5][C:4]([CH3:12])([CH3:11])[NH:3]1.S(=O)(=O)(O)O.[C:19](O)(=O)[CH3:20]>>[CH2:19]([CH:20]1[NH:9][CH2:8][C:6]2([CH2:5][C:4]([CH3:12])([CH3:11])[NH:3][C:2]([CH3:13])([CH3:1])[CH2:7]2)[O:10]1)[CH2:2][CH2:7][CH2:6][CH2:5][CH:4]([CH3:12])[CH3:11]

Participants

4

Reactant 3

HCID 176Acetic AcidHCID 1118Sulfuric Acid2×HCID 908744-Piperidinecarbonitrile, 4-hydroxy-2,2,6,6-tetramethyl-

Product 1

HCID 23344265HCID 23344265, compound

Procedure

182 g of 2,2,6,6-tetramethyl-4-hydroxy-4-cyanopiperidine, 284 g of isononyl-aldehyde and 200 g of concentrated sulfuric acid are stirred for 25 hours at 60° C. in 600 g of glacial acetic acid in a 2 liter apparatus with agitator. After cooling the main portion of the solvent is distilled off under reduced pressure. The residue is stirred with 500 ml of acetone and suction-filtered, thus yielding 292 g=69% of th. of the sulfuric acid salt of the intended compound.

Workup

  1. temperatureAfter cooling the main portion of the solvent
  2. distillationis distilled off under reduced pressure
  3. filtrationsuction-filtered
  4. customthus yielding 292 g=69% of th

Sources & evidence

ORD record
ord-c2fadbb5f2ca4eb892744daef57bea8d
Source dataset
uspto-grants-1980_09
Patent number
US04220773

Reaction notes

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