HCID 12053659, compound → 6,6'-Di-tert-butyl-2,2'-thiodi-p-cresol

HRID 272263Notes

Reaction equation

HRID 272263 reaction equation
[C:1]([C:5]1[C:6]([O:25]CC)=[C:7]([S:12][C:13]2[CH:18]=[C:17]([CH3:19])[CH:16]=[C:15]([C:20]([CH3:23])([CH3:22])[CH3:21])[C:14]=2[OH:24])[CH:8]=[C:9]([CH3:11])[CH:10]=1)([CH3:4])([CH3:3])[CH3:2].C(C1C(O)=C(SC2C=C(C)C=C(C(C)(C)C)C=2OC)C=C(C)C=1)(C)(C)C.C(C1C(O)=C(SC2C=C(C)C=C(C(C)(C)C)C=2OCCC)C=C(C)C=1)(C)(C)C.C(C1C(O)=C(SC2C=C(C)C=C(C(C)(C)C)C=2O[Si](C)(C)C)C=C(C)C=1)(C)(C)C.C(C1C(O)=C(SC2C(C)=CC=CC=2C)C=C(C(C)(C)C)C=1)(C)(C)C>>[S:12]([C:13]1[CH:18]=[C:17]([CH3:19])[CH:16]=[C:15]([C:20]([CH3:23])([CH3:22])[CH3:21])[C:14]=1[OH:24])[C:7]1[CH:8]=[C:9]([CH3:11])[CH:10]=[C:5]([C:1]([CH3:4])([CH3:2])[CH3:3])[C:6]=1[OH:25]

Participants

6

Reactant 5

HCID 12053659HCID 12053659, compound2×HCID 713615722,4-Di-tert-butyl-6-[(2,6-dimethylphenyl)sulfanyl]phenolHCID 86593619HCID 86593619, compoundHCID 86593620HCID 86593620, compoundHCID 86593621HCID 86593621, compound

Product 1

HCID 666616,6'-Di-tert-butyl-2,2'-thiodi-p-cresol

Procedure

Preferably, the ligand is (3-tert-butyl-2-ethoxy-5-methylphenyl)(3-tert-butyl-2-hydroxy-5-methylphenyl)sulfide, (3-tert-butyl-2-hydroxy-5-methylphenyl)(3-tert-butyl-2-methoxy-5-methylphenyl)sulfide, (3-tert-butyl-2-hydroxy-5-methylphenyl)(3-tert-butyl-2-n-propoxy-5-methylphenyl)sulfide, (3-tert-butyl-2-hydroxy-5-methylphenyl)(3-tert-butyl-5-methyl-2-trimethylsiloxyphenyl)sulfide or (3,5-di-tert-butyl-2-hydroxyphenyl)(2,6-dimethylphenyl) sulfide. The most preferred ligand is (3-tert-butyl-2-hydroxy-5-methylphenyl)(3-tert-butyl-2-methoxy-5-methylphenyl)sulfide.

Sources & evidence

ORD record
ord-83cfc79ecc024c1db34e8cdb2ab02b1a
Source dataset
uspto-grants-2008_11
Patent number
US07456127B2

Reaction notes

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